Mankhwala ambiri odziwika bwino ochokera ku zitsamba, kuphatikizapo tiyi wobiriwira ndi ginkgo biloba, amatha kuyanjana ndi mankhwala operekedwa ndi dokotala, malinga ndi ndemanga yatsopano ya kafukufuku yomwe idasindikizidwa mu British Journal of Clinical Pharmacology. Kuyanjana kumeneku kungapangitse kuti mankhwalawa asagwire ntchito bwino komanso akhoza kukhala oopsa kapena oopsa.
Madokotala akudziwa kuti zitsamba zimatha kusintha njira zochizira, ofufuza ochokera ku Medical Research Council of South Africa akulemba mu pepala latsopano. Koma chifukwa anthu nthawi zambiri sauza ogwira ntchito zachipatala awo mankhwala ndi zowonjezera zomwe akumwa, zakhala zovuta kwa asayansi kudziwa mankhwala ndi zowonjezera zomwe ayenera kupewa.
Ndemanga yatsopanoyi idasanthula malipoti 49 okhudza zotsatira zoyipa za mankhwala ndi maphunziro awiri owonera. Anthu ambiri omwe adawunikidwawo anali kulandira chithandizo cha matenda a mtima, khansa, kapena kusamutsidwa kwa impso ndipo anali kumwa warfarin, statins, mankhwala a chemotherapy, kapena mankhwala oletsa chitetezo chamthupi. Ena anali ndi kupsinjika maganizo, nkhawa, kapena matenda amitsempha ndipo analandira mankhwala oletsa kuvutika maganizo, mankhwala oletsa kusokonezeka maganizo, kapena mankhwala oletsa kugwedezeka.
Kuchokera ku malipoti awa, ofufuza adapeza kuti kuyanjana kwa mankhwala azitsamba ndi mankhwala kunali "kothekera" mu 51% ya malipoti ndipo "kothekera kwambiri" mu pafupifupi 8% ya malipoti. Pafupifupi 37% adatchulidwa ngati kuyanjana kwa mankhwala azitsamba, ndipo 4% yokha ndi omwe amaonedwa kuti ndi okayikitsa.
Mu lipoti lina, wodwala yemwe ankamwa mankhwala a statin anadandaula za kupweteka kwambiri kwa miyendo ndi kupweteka atamwa makapu atatu a tiyi wobiriwira patsiku, zomwe zimachitika kawirikawiri. Ofufuzawo analemba kuti izi zinachitika chifukwa cha momwe tiyi wobiriwira umakhudzira kuchuluka kwa ma statin m'magazi, ngakhale adati kafukufuku wowonjezereka akufunika kuti apeze zifukwa zina zomwe zingachitike.
Mu lipoti lina, wodwalayo anamwalira atagwidwa ndi khunyu akusambira, ngakhale kuti ankamwa mankhwala oletsa khunyu nthawi zonse kuti achiritse vutoli. Komabe, kafukufuku wa mtembo wake unasonyeza kuti anali atachepetsa kuchuluka kwa mankhwala amenewa m'magazi, mwina chifukwa cha mankhwala owonjezera a ginkgo biloba omwe ankamwanso nthawi zonse, omwe anakhudza kagayidwe kawo ka thupi.
Kumwa mankhwala owonjezera ochokera ku zitsamba kwakhalanso kogwirizana ndi zizindikiro zoipitsitsa za kuvutika maganizo mwa anthu omwe akumwa mankhwala ochepetsa nkhawa, komanso kukana ziwalo mwa anthu omwe adaikidwa impso, mtima, kapena chiwindi, olembawo adalemba m'nkhaniyi. Kwa odwala khansa, mankhwala a chemotherapy awonetsedwa kuti amagwirizana ndi mankhwala owonjezera ochokera ku zitsamba, kuphatikizapo ginseng, echinacea, ndi madzi a chokeberry.
Kusanthulako kunawonetsanso kuti odwala omwe akumwa warfarin, yomwe ndi mankhwala ochepetsa magazi, adanenanso kuti "pali kuyanjana kwakukulu pakati pa matenda." Ofufuza akuganiza kuti zitsambazi zitha kusokoneza kagayidwe ka warfarin, motero kuchepetsa mphamvu yake yoletsa magazi kulowa m'magazi kapena kuyambitsa kutuluka magazi.
Olembawo akuti maphunziro ambiri a labotale ndi kufufuza mosamala mwa anthu enieni akufunika kuti apereke umboni wamphamvu wokhudzana ndi kuyanjana pakati pa zitsamba ndi mankhwala enaake. "Njira imeneyi idziwitsa akuluakulu oyang'anira mankhwala ndi makampani opanga mankhwala kuti asinthe zambiri zolembedwa kutengera zomwe zilipo kuti apewe zotsatirapo zoyipa," adalemba.
Amakumbutsanso odwala kuti nthawi zonse ayenera kuuza madokotala ndi akatswiri a mankhwala za mankhwala aliwonse kapena zowonjezera zomwe akumwa (ngakhale zinthu zogulitsidwa ngati zachilengedwe kapena zamasamba), makamaka ngati apatsidwa mankhwala atsopano.