Makhungu ndi mbewu za mphesa ndi zipatso zimakhala ndi resveratrol, zomwe zimapangitsa vinyo wofiira kukhala wochuluka mu mankhwalawa. Kafukufuku akusonyeza kuti ali ndi ubwino waukulu pa thanzi, koma muyenera kudziwa zambiri za kuchuluka kwa zowonjezera zomwe muyenera kumwa.
Ngati munamvapo kuti vinyo wofiira amathandiza kuchepetsa cholesterol, ndiye kuti mwina munamvapo za resveratrol, chinthu chomwe chimatchuka kwambiri mu vinyo wofiira.
Koma kuwonjezera pa kukhala gawo lothandiza la vinyo wofiira ndi zakudya zina, resveratrol ilinso ndi mphamvu pa thanzi.
Ndipotu, zowonjezera za resveratrol zimagwirizanitsidwa ndi maubwino ambiri azaumoyo, kuphatikizapo kuteteza ntchito ya ubongo ndi kuchepetsa kuthamanga kwa magazi (1, 2, 3, 4).
Nkhaniyi ikufotokoza zomwe muyenera kudziwa zokhudza resveratrol, kuphatikizapo zabwino zake zisanu ndi ziwiri zomwe zingathandize pa thanzi.
Resveratrol ndi chomera chomwe chimagwira ntchito ngati antioxidant. Zakudya zazikulu zomwe zimapezeka ndi vinyo wofiira, mphesa, zipatso zina, ndi mtedza (5, 6).
Kapangidwe kameneka kamakhala m'makoswe ndi mbewu za mphesa ndi zipatso. Zigawo izi za mphesa zimakhudzidwa ndi kuwiritsa kwa vinyo wofiira ndipo motero zimakhala ndi resveratrol yambiri (5, 7).
Komabe, kafukufuku wambiri wa resveratrol wachitika m'zinyama ndi m'machubu oyesera pogwiritsa ntchito mankhwala ambiri awa (5, 8).
Pa maphunziro ochepa omwe anachitika mwa anthu, ambiri ayang'ana kwambiri mitundu yowonjezera ya mankhwalawa, yomwe imapezeka m'magulu apamwamba kuposa omwe amapezeka kuchokera ku chakudya (5).
Resveratrol ndi mankhwala ophera antioxidant omwe amapezeka mu vinyo wofiira, zipatso ndi mtedza. Kafukufuku wambiri wa anthu wagwiritsa ntchito zowonjezera zomwe zili ndi resveratrol yambiri.
Chifukwa cha mphamvu zake zoletsa ma antioxidants, resveratrol ikhoza kukhala chowonjezera chabwino chochepetsera kuthamanga kwa magazi (9).
Ndemanga ya mu 2015 inanena kuti kuchuluka kwa mankhwala ochulukirapo kungathandize kuchepetsa kupsinjika kwa mitsempha yamagazi pamene mtima ukugunda (3).
Kupanikizika kumeneku kumatchedwa systolic blood pressure ndipo kumawoneka ngati chiwerengero chachikulu mu kuwerenga kwa kuthamanga kwa magazi.
Kuthamanga kwa magazi m'thupi nthawi zambiri kumawonjezeka ndi ukalamba chifukwa cha matenda a atherosclerosis. Ngati kuli kokwera, ndiye kuti kumayambitsa matenda a mtima.
Resveratrol ingathandize kuchepetsa kuthamanga kwa magazi mwa kuthandiza kupanga nitric oxide yambiri, yomwe imapangitsa kuti mitsempha yamagazi ipumule (10, 11).
Komabe, olemba kafukufukuyu adati kafukufuku wowonjezereka akufunika kuti apereke malingaliro enieni pa mlingo woyenera wa resveratrol kuti uthandize kwambiri kuthamanga kwa magazi.
Kafukufuku wochuluka wa nyama wasonyeza kuti zowonjezera za resveratrol zimatha kusintha mafuta m'magazi m'njira zabwino (12, 13).
Mu kafukufuku wa 2016, mbewa zinadyetsedwa zakudya zokhala ndi mapuloteni ambiri ndi mafuta ambiri ochulukirapo omwe amawonjezeredwa ndi resveratrol.
Ofufuzawo adapeza kuti kuchuluka kwa cholesterol yonse ndi kulemera kwa thupi la mbewa kunachepa, pomwe kuchuluka kwa cholesterol "yabwino" ya HDL kunakwera (13).
Zikuoneka kuti resveratrol imakhudza kuchuluka kwa cholesterol mwa kuchepetsa ntchito ya ma enzyme omwe amalamulira kupanga cholesterol (13).
Monga antioxidant, imachepetsanso okosijeni wa cholesterol "yoyipa" ya LDL. Kuchuluka kwa okosijeni wa LDL kumabweretsa mapangidwe a plaque mu khoma la mitsempha yamagazi (9, 14).
Pambuyo pa miyezi isanu ndi umodzi ya chithandizo, omwe adatenga mphesa yosakhala yokhazikika kapena placebo adatsika ndi 4.5% mu LDL ndipo 20% mu LDL yosungunuka idatsika (15).
Zakudya zowonjezera za Resveratrol zingathandize kuchepetsa kuchuluka kwa mafuta m'magazi mwa nyama. Popeza ndi antioxidant, zimachepetsanso kukhuthala kwa cholesterol ya LDL.
Kuthekera kwa mankhwala owonjezera moyo wa zamoyo zosiyanasiyana kwakhala gawo lalikulu la kafukufuku (16).
Pali umboni wakuti resveratrol imayambitsa majini ena, motero imaletsa matenda okalamba (17).
Izi zimagwira ntchito mofanana ndi kuchepetsa ma calories, zomwe zasonyeza zotsatira zabwino pakuwonjezera moyo mwa kusintha momwe majini amaonekera (18, 19).
Kuwunikanso kafukufuku wofufuza ulalowu kunapeza kuti resveratrol inakulitsa moyo wa munthu mu 60% ya zamoyo zomwe zinaphunziridwa, koma zotsatira zake zinali zoonekera kwambiri m'zamoyo zomwe sizili pafupi ndi anthu, monga nyongolotsi ndi nsomba (20).
Kafukufuku wa zinyama wasonyeza kuti zowonjezera za resveratrol zitha kutalikitsa moyo. Komabe, sizikudziwika ngati zingakhale ndi zotsatira zofanana kwa anthu.
Kafukufuku wambiri wasonyeza kuti kumwa vinyo wofiira kungathandize kuchepetsa kuchepa kwa chidziwitso chifukwa cha ukalamba (21, 22, 23, 24).
Zikuoneka kuti zimasokoneza zidutswa za mapuloteni otchedwa amyloid beta, zomwe ndizofunikira kwambiri popanga ma plaque a matenda a Alzheimer's (21, 25).
Ngakhale kafukufukuyu ndi wosangalatsa, asayansi akadali ndi mafunso okhudza mphamvu ya thupi yogwiritsira ntchito resveratrol yowonjezera, zomwe zimalepheretsa kugwiritsidwa ntchito nthawi yomweyo ngati chowonjezera choteteza ubongo (1, 2).
Resveratrol ndi mankhwala amphamvu oletsa kutupa komanso antioxidant omwe angateteze maselo a muubongo kuti asawonongeke.
Ubwino uwu umaphatikizapo kukulitsa chidwi cha insulin komanso kupewa mavuto a shuga (26,27,28,29).
Kufotokozera kwina kwa momwe resveratrol imagwirira ntchito ndikuti imatha kuletsa enzyme kusasintha shuga kukhala sorbitol, shuga mowa.
Pamene sorbitol yochuluka imadziunjikira m'matupi a anthu odwala matenda a shuga, ingayambitse kupsinjika kwa okosijeni komwe kumawononga maselo (30, 31).
Resveratrol ingathandizenso anthu odwala matenda ashuga kuposa anthu omwe alibe matenda ashuga. Mu kafukufuku wina wa nyama, vinyo wofiira ndi resveratrol zinapezeka kuti ndi mankhwala amphamvu kwambiri ophera antioxidants m'makoswe a shuga kuposa m'makoswe omwe alibe matenda ashuga (32).
Ofufuza akuti mankhwalawa angagwiritsidwe ntchito pochiza matenda a shuga ndi mavuto ake mtsogolo, koma kafukufuku wowonjezereka akufunika.
Resveratrol imathandiza mbewa kuti zizitha kuyankha bwino insulin komanso kuthana ndi mavuto a matenda a shuga. M'tsogolomu, odwala matenda a shuga angapindulenso ndi mankhwala a resveratrol.
Mankhwala owonjezera a zitsamba akuphunziridwa ngati njira yochiritsira ndikuletsa kupweteka kwa mafupa. Akagwiritsidwa ntchito ngati mankhwala owonjezera, resveratrol ingathandize kuteteza khungu kuti lisasweke (33, 34).
Kafukufuku wina adabaya resveratrol m'malo olumikizirana mawondo a akalulu a nyamakazi ndipo adapeza kuti akalulu awa anali ndi vuto lochepa la cartilage (34).
Kafukufuku wina wa m'chubu choyesera ndi nyama wasonyeza kuti mankhwalawa amatha kuchepetsa kutupa ndikuletsa kuwonongeka kwa mafupa (33, 35, 36, 37).
Resveratrol yaphunziridwa chifukwa cha mphamvu yake yopewera ndi kuchiza khansa, makamaka m'machubu oyesera. Komabe, zotsatira zake zasakanikirana (30, 38, 39).
Zawonetsedwa kuti zimalimbana ndi maselo osiyanasiyana a khansa m'maphunziro a nyama ndi ma test tube, kuphatikizapo khansa ya m'mimba, m'matumbo, pakhungu, m'mawere, ndi prostate (40, 41, 42, 43, 44).
Komabe, popeza maphunzirowa achitika mpaka pano m'machubu oyesera komanso m'zinyama, kafukufuku wowonjezereka akufunika kuti amvetsetse ngati mankhwalawa angagwiritsidwe ntchito komanso momwe angachiritsire khansa mwa anthu.
Kafukufuku wogwiritsa ntchito zowonjezera za resveratrol sanapeze zoopsa zilizonse. Zikuoneka kuti anthu athanzi amatha kuzilekerera bwino (47).
Komabe, ziyenera kudziwika kuti pakadali pano palibe malangizo omveka bwino okhudza kuchuluka kwa resveratrol yomwe munthu ayenera kumwa kuti apeze ubwino wathanzi.
Palinso machenjezo ena, makamaka okhudza momwe resveratrol imagwirira ntchito ndi mankhwala ena.
Popeza kuti milingo yambiri yasonyezedwa kuti imaletsa magazi kuundana m'machubu oyesera, imatha kuwonjezera kutuluka magazi kapena kuvulala ikamwedwa ndi mankhwala oletsa magazi kuundana monga heparin kapena warfarin, kapena mankhwala ena opweteka (48, 49).
Resveratrol imaletsanso ma enzyme omwe amathandiza kuchotsa zinthu zina m'thupi. Izi zikutanthauza kuti mankhwala ena amatha kufika pamlingo wosatetezeka. Izi zikuphatikizapo mankhwala ena ochepetsa kuthamanga kwa magazi, mankhwala oletsa nkhawa, ndi mankhwala oletsa chitetezo chamthupi (50).
Ngati mukumwa mankhwala pakali pano, mungafune kulankhula ndi dokotala wanu musanamwe resveratrol.