Arachidonic acid (ARA), docosahexaenoic acid (DHA) ndi eicosapentaenoic acid (EPA) ndi ma chain polyunsaturated fatty acids (LCPUFA). Carotenoids, kuphatikiza lutein ndi zeaxanthin (LZ), amapezeka makamaka m'masamba obiriwira.
ARA ndi DHA ndi zochuluka mu ubongo ndipo ndi zigawo zikuluzikulu za phospholipids. Kafukufuku wasonyeza kuti kuwonjezera pa mlingo waukulu wa DHA ndi EPA kungathandize kukumbukira ntchito ya okalamba.
Kuonjezera apo, LZ, chigawo cha antioxidant cha ubongo, chanenedwa kuti chimakhala ndi chitetezo pamaselo a mitsempha, motero zimakhudza ntchito ya chidziwitso. Komabe, mphamvu ya lutein ndi zeaxanthin pa ntchito yokumbukira sizikudziwika bwino chifukwa cha zotsatira zotsutsana kuchokera ku maphunziro am'mbuyomu.
Kutengera kuti ARA, DHA, EPA, L ndi Z (LCPUFA + LZ) amapezeka muubongo, komanso malipoti ena okhudza kukumbukira bwino, olemba kafukufuku wapano adanenanso kuti kuphatikiza kwa zinthu izi kumatha kusintha. kukumbukira. ntchito mu ubongo. achikulire athanzi.
Ofufuza a ku Japan adachita kafukufuku wa masabata a 24, osasintha, akhungu awiri, oyendetsedwa ndi placebo, omwe amatsatira gulu lofanana la zotsatira za LCPUFA + LH pa ntchito yokumbukira anthu achikulire a ku Japan omwe ali ndi vuto la kukumbukira koma opanda dementia.
Sanapeze kusiyana kwakukulu pakati pa magulu. Komabe, pofufuza pamodzi gulu la anthu omwe ali ndi chidziwitso chochepa, kusintha kwakukulu kunawonedwa.
Lipotilo linamaliza kuti: “Kafukufukuyu akusonyeza kwa nthawi yoyamba kuti kuphatikiza kwa LCPUFA ndi LZ kungathandize kuti anthu achikulire athanzi a ku Japan azitha kukumbukira zinthu koma opanda matenda a maganizo.” 'mawu ad1'); });
Chiwerengero cha anthu a 120 ochokera ku Tokyo ndi madera ozungulira adasinthidwa kukhala magulu atatu: (1) gulu la placebo likulandira placebo monga chakudya chowonjezera; (2) gulu la placebo likulandira placebo monga chowonjezera cha zakudya; (2)). Gulu la LCPUFA + X lomwe lidalandira chowonjezera chazakudya chokhala ndi LCPUFA (yokhala ndi 120 mg ARA, 300 mg DHA ndi 100 mg EPA patsiku) ndi Compound X (yosasonyezedwa ngati chigawo ichi sichinali phunziro la phunziroli) ) (3) LCPUFA +LH gulu lolandira chakudya chowonjezera chokhala ndi LCPUFA (120mg ARA, 300mg DHA ndi 100mg EPA patsiku) kuphatikiza LH (10mg lutein ndi 2mg zeaxanthin patsiku).
Zakudya zoyesera ndi zopangira za kafukufukuyu zidaperekedwa ndi Suntory Health Co., Ltd., yomwe imagulitsa zakudya zathanzi zomwe zili ndi LCPUFA.
Wechsler Logical Memory Scale II (WMS-R LM II) yokonzedwanso ndi Montreal Cognitive Test mu Japanese (MoCA-J) anagwiritsidwa ntchito pounika.
Zaka, jenda, ndi maphunziro zidalembedwa ngati mikhalidwe ya omwe adatenga nawo gawo. Zitsanzo za magazi zinasonkhanitsidwa poyambira, masabata 12 ndi 24 a mafuta acid ndi LZ kusanthula.
Kuyesedwa kwa Neuropsychological kunachitika ndipo kudya kwamafuta amafuta kumayesedwa poyambira, pa 12 ndi 24 milungu. Wotenga nawo mbali aliyense adamaliza diary, ndikulemba zina zowonjezera ndikuwona kusintha kwakukulu kwa moyo.
Zomwe zapezedwa zikuwonetsa kuti LCPUFA + LZ inalibe chidwi chokhudza kukumbukira kwa anthu achikulire athanzi aku Japan omwe ali ndi vuto la kukumbukira, koma chowonjezeracho chinathandizira kukumbukira ntchito kwa omwe ali ndi chidziwitso chochepa.
Olembawo amanena kuti maphunziro amtsogolo okhudzidwa ndi chidziwitso chodziwika bwino cha chidziwitso cha otenga nawo mbali pazidziwitso zoyambira zidzathandiza kupanga ziganizo zoyenera za zotsatira za kulowererapo pa ntchito yokumbukira.
"Zotsatira zamafuta amtundu wautali wa polyunsaturated fatty acids kuphatikiza lutein ndi zeaxanthin pa kukumbukira kwa episodic mwa okalamba athanzi"
Sueyasu, T., Yasumoto, K., Tokuda, H., Kaneda, Y.;
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