Arachidonic acid (ARA), docosahexaenoic acid (DHA) ndi eicosapentaenoic acid (EPA) ndi ma polyunsaturated fatty acids a unyolo wautali (LCPUFA). Ma carotenoids, kuphatikizapo lutein ndi zeaxanthin (LZ), amapezeka kwambiri mu ndiwo zamasamba zobiriwira.
ARA ndi DHA zili zambiri muubongo ndipo ndi zigawo zazikulu za phospholipids. Kafukufuku wasonyeza kuti kuwonjezera pa DHA ndi EPA zambiri kungathandize okalamba kugwira ntchito yokumbukira.
Kuphatikiza apo, LZ, gawo la ubongo lomwe limagwiritsa ntchito antioxidant, lanenedwa kuti limateteza maselo amitsempha, motero limakhudza ntchito ya ubongo. Komabe, kugwira ntchito kwa lutein ndi zeaxanthin pa ntchito yokumbukira sikukudziwika bwino chifukwa cha zotsatira zotsutsana kuchokera ku maphunziro am'mbuyomu.
Kutengera mfundo yakuti ARA, DHA, EPA, L ndi Z (LCPUFA + LZ) zilipo muubongo, komanso malipoti ena okhudza ntchito yokumbukira bwino, olemba kafukufukuyu adanenanso kuti kuphatikiza kwa zinthuzi kungathandize anthu okalamba athanzi kukumbukira bwino.
Ofufuza aku Japan adachita kafukufuku wa masabata 24, wosankhidwa mwachisawawa, wowona kawiri, wolamulidwa ndi placebo, komanso wokhudzana ndi zotsatira za LCPUFA + LH pa ntchito yokumbukira mwa okalamba athanzi aku Japan omwe ali ndi vuto lokumbukira koma opanda matenda a dementia.
Sanapeze kusiyana kwakukulu pakati pa maguluwa. Komabe, pofufuza pamodzi gulu la ophunzira omwe ali ndi vuto la kuzindikira, kusintha kwakukulu kunawonedwa.
Lipotilo likumaliza kuti: “Kafukufukuyu akusonyeza koyamba kuti kuphatikiza kwa LCPUFA ndi LZ kungathandize kuti kukumbukira kukhale bwino mwa achikulire athanzi aku Japan omwe ali ndi vuto la kuzindikira koma opanda matenda amisala.” ‘text ad1′); });
Anthu 120 ochokera ku Tokyo ndi madera ozungulira adasankhidwa mwachisawawa m'magulu atatu: (1) gulu la placebo lomwe lidalandira placebo ngati chowonjezera pazakudya; (2) gulu la placebo lomwe lidalandira placebo ngati chowonjezera pazakudya; (2)). Gulu la LCPUFA+X lomwe lidalandira chowonjezera pazakudya chokhala ndi LCPUFA (chokhala ndi 120 mg ya ARA, 300 mg ya DHA ndi 100 mg ya EPA patsiku) ndi Compound X (siinawonetsedwe chifukwa chowonjezera ichi sichinali mutu wa kafukufukuyu)) (3) Gulu la LCPUFA+LH lomwe lidalandira chowonjezera pazakudya chokhala ndi LCPUFA (120mg ya ARA, 300mg ya DHA ndi 100mg ya EPA patsiku) pamodzi ndi LH (10mg ya lutein ndi 2mg ya zeaxanthin patsiku).
Chakudya ndi zinthu zina zoyesera za kafukufukuyu zinaperekedwa ndi Suntory Health Co., Ltd., yomwe imagulitsa zakudya zopatsa thanzi zomwe zili ndi LCPUFA.
Wechsler Logical Memory Scale II (WMS-R LM II) yosinthidwa ndi Montreal Cognitive Test mu Chijapani (MoCA-J) zinagwiritsidwa ntchito poyesa.
Zaka, jenda, ndi maphunziro zinalembedwa ngati makhalidwe a ophunzirawo. Zitsanzo za magazi zinasonkhanitsidwa kumayambiriro kwa sabata, masabata 12 ndi 24 kuti akafufuze mafuta ndi LZ.
Kuyezetsa kwa ubongo ndi maganizo kunachitika ndipo kudya mafuta acid m'zakudya kunayesedwa koyambirira, pa masabata 12 ndi 24. Wophunzira aliyense adalemba dayalo, kulemba zakudya zina ndikuwona ngati pali kusintha kwakukulu pa moyo wake.
Zomwe zapezeka zasonyeza kuti LCPUFA + LZ sinakhudze kwambiri ntchito yokumbukira mwa anthu achikulire athanzi aku Japan omwe ali ndi vuto la kukumbukira, koma chowonjezeracho chinathandiza ntchito yokumbukira mwa anthu omwe ali ndi vuto la kuzindikira.
Olembawo akuti maphunziro amtsogolo okhudza kulowererapo pogwiritsa ntchito chidziwitso chatsatanetsatane cha momwe ophunzirawo amagwirira ntchito pozindikira zinthu adzathandiza kupanga zigamulo zoyenera zokhudza momwe kulowererapoko kumakhudzira ntchito yokumbukira.
"Zotsatira za ma polyunsaturated fatty acids a unyolo wautali pamodzi ndi lutein ndi zeaxanthin pa kukumbukira kwa episodic mwa okalamba athanzi"
Sueyasu, T., Yasumoto, K., Tokuda, H., Kaneda, Y.;
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