Mu dziko la zowonjezera zachilengedwe za thanzi, rutin ikudziwika mwachangu ngati mankhwala amphamvu a phytochemical. Liwu lochokera ku liwu lachilatini lakuti 'ruta', lomwe limatanthauza 'rue', mankhwalawa akhala akufufuzidwa kwambiri chifukwa cha ubwino wake waukulu pa thanzi.

Rutin, yomwe imadziwikanso kuti 芸香苷or芦丁, ndi chinthu chachilengedwe chomwe chimapezeka m'maluwa a dzungu. Ndi chinthu chofunikira kwambiri pakusunga thanzi labwino la mtima ndi mitsempha yamagazi. Ntchito yayikulu ya chinthuchi ndikuletsa kutuluka magazi ndikuyendetsa bwino magazi, zomwe zimathandiza kuti mtima ugwire bwino ntchito komanso ukhale wathanzi.

Njira yolekanitsa ndi kuyeretsa rutin ndi yovuta ndipo imafuna njira zapamwamba monga High Performance Liquid Chromatography (HPLC). Chomerachi chikugwiritsidwa ntchito kwambiri mu zakudya zowonjezera chifukwa chili ndi maubwino ambiri azaumoyo, kuyambira chitetezo cha mtima mpaka chitetezo chamthupi cholimba.

Kafukufuku wambiri wachitika pa mankhwala a rutin, zomwe zatsimikiziranso ubwino wake pa thanzi. Zawonetsedwa kuti ali ndi mphamvu zotsutsana ndi kutupa, zomwe zimapangitsa kuti azithandiza polimbana ndi matenda monga nyamakazi. Kuphatikiza apo, rutin yapezeka kuti ili ndi mphamvu zotsutsana ndi kutupa, kumenyana ndi ma free radicals komanso kuchepetsa kupsinjika kwa okosijeni. Izi zingathandize kupewa matenda osatha monga khansa ndi matenda a mtima.

Tsogolo la rutin likuwoneka losangalatsa pamene anthu ambiri akuyamba kuzindikira ubwino wake pa thanzi. Pamene kafukufuku akupitiliza kufufuza mozama za makhalidwe a chinthu chodabwitsachi, tikuyembekeza kuwona ntchito zambiri za rutin m'munda wa thanzi lachilengedwe ndi mankhwala.

Pomaliza, rutin ndi mankhwala odabwitsa omwe amapereka maubwino osiyanasiyana pa thanzi. Kuthekera kwake kupewa kutuluka magazi, kukonza kuyenda kwa magazi, komanso kuthandizira thanzi la mtima kumapangitsa kuti ikhale chida champhamvu kwambiri pakusunga thanzi labwino la mtima. Ndi kafukufuku wopitilira komanso chidziwitso chowonjezeka, rutin idzakhala ndi gawo lofunika kwambiri pakulimbikitsa thanzi labwino komanso kupewa matenda osatha m'zaka zikubwerazi.